Actually named Cayo Macho but renamed for the tourist trade, this is a iguana reserve on a desert island - basically Galapagos on a budget. The iguanas are completely unafraid of people and just hang around waiting for your meal leftovers like a bunch of scaly pigeons. There's also some extremely cute giant tree rats (they are cute, honestly) and the biggest hermit crabs I've ever seen. Well worth the two hour boat trip from Trinidad.
Cayo Macho is a nature reserve off the coast of Cuba not far from Trinidad. It has only one old guy living there to look after the endanged lizards, which are quite tame and will happily run over your feet. It takes around 45 minutes to walk around the island, but watch out for the stretches of path covered with baby crabs.
Catch a ferry from from Trinidad.
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