The country is small so you can reach any place in Israel (well almost) in a few hours drive from Tel Aviv.
Tel Aviv by far has the best services, entertainment, hotels, and restaurants compared to any other Israeli city. Even if you don't like the hustle and bustle of a large city (the Tel Aviv metropolitan area has more than two million people) you should still consider the convenience.
And if you are into cities that never sleep (like Madrid and New York) then there are few that can compete with Tel Aviv.
The people are friendly and helpful, most speak English, crime is low (so you don't have to worry about walking at night), and the weather is warm and sunny most of the year.
Another tip: Don't miss historic Jaffa (located in southern Tel Aviv). Great shops, clubs, food, and the biggest outdoor flea market I've ever seen.
My daughter loves Tel Aviv (and I do too).
Check out some photos at: www.pbase.com/gilazouri/telaviv
Tel Aviv is on the Mediterranean coast, more-or-less in the centre of the country.
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