After a hard week schlepping across country in crowded taxi brousses and struggling through jungle to spot lemurs, you will need to relax. Fly out to the Ile St Marie (fly - believe me you do NOT want to entrust your life to the small boats) and chill for a week.
You can have accommodation from the cheap (Chez Regine on the tiny Ile aux Nattes at the tip of the island is fabulous; the chicken and rice in the restaurant is sublime) or the sublime (Princess Bora lodge run by whale enthusiast "Fifou" Mayer). Imagine the Maldives without all the muppets. Amazing beaches, huge lagoon to snorkel in, humpback whale watching in season.
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