The combined streets of Rue de la Conféderation, Rue du Rhône and Rue de la Croix d'or are lined with some of the most expensive shops in Switzerland (the others being in Zurich) so if you have serious Swiss francs to burn than this area is the place to go, otherwise it's great just to look at those watches and clothes which you can't have. Even the brand name stores of H&M and C&A are not as cheap as you may think they are.
There are numerous undercover shopping malls just off each street too which are great places to escape from the summer heat.
The Rue de la Conféderation is a 20 min walk from Cornavin train station, just follow Rue du Mont Blanc, cross the Rhône river via the Pont Mont Blanc and turn into Rue de la Conféderation which becomes the Rue de la Croix d'or and then becomes the Rue du Rhône
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