This is a nice and lively brewery pub. The beer is served in tiny glasses, but not to worry: empty ones are contantly replaced, until you cover your glass with your beermat to signal you've had enough.

They also serve nice local food.
During daytime they do guided tours of the brewery itself, but you'd need to arrange that beforehand (and you need at least 15 people).

Calwer Straße 31, just across from the shopping mall 'Calwer Passage,' in a pedestrian area in the city centre;
tel: 0711-2224944-12;
www.calwereck.de;
S-Bahn: Stadtmitte, then take the Rotebühlplatz/Calwer Straße exit

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