A beautiful winery, off the beaten track in Sonoma Valley, which is a short (2-3 hour) drive from San Francisco. The reason I choose this winery over all the others is that they are the only winery that I know of that pairs hors d'oeuvres with each wine you taste. The taste of the food really brings out the flavours of the wines, making for an enhanced wine-tasting experience. The winery is also near the gorgeous Alexander Valley, famous for its Zinfandels and its stunning scenery, much more rustic and picturesque than commercial Napa Valley.
I suggest either hiring a car in SF and spending a day driving around the area, or booking yourself onto a wine-tasting tour/limousine, obviously allowing you to sample more of the region's produce.
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