Sephardic Jews actually made up the majority of Thessaloniki's population from 1600 to WW2, and the Jewish museum is a fascinating and unique account of an extroardinary story, as well as the general history of the city in that period.
If your interested in the history check out the Thessaloniki page on Wikipedia: en.wikipedia.org/wiki/Thessaloniki
13, Agiou Mina Street, 546 24 Thessaloniki, Greece
tel/fax: +30 2310 250406-7;
www.jmth.gr